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triose phosphate isomerase

Branka Mijatov

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How does triose phosphate isomerase deficiency biochemically impaire body functions? I understand that deficiency of this enzyme leads to accumulation of Dihydroxyacetone phosphate, which cannot be converted to Glyceraldehyde 3-phosphate in Glycolysis. But what then happens to this accumulated Dihydroxyacetone phosphate?

 


   
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