Lou Johnson
I have had better results with 5 Ultram, 2 at breakfast, 2 at lunch, 1 and 1 Vioxx at dinner and 1 Mirapex about 9 p.m. I had been tried on almost everything known for RLS. Sinemet caused rebound, etc. I would take two Ultram at dinner before being put on Vioxx for Arthritis. This has been almost a Miracle for me. I was put on Ultram for back pain, and realized my RLS was improving, so gradually got off all the Sinemet, which was causing augmentation and rebound. Hope this helps someone, as I don't think there is anything worse than a severe case of RLS.